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Background
Varicocoele is a swollen bulge of the pampiniform venous plexus inside the scrotum. It is also considered one of the causes of infertility in males. It has been demonstrated that hesperidin has remarkable pharmacological potentials, including antioxidant, anti‐inflammatory, antimicrobial, and anticarcinogenic effects.
Objective
The present study aimed to evaluate the protective effect...
Background
This case control study aimed to investigate whether symptoms of sexual dysfunction are more common in males from infertile couples than in the general population and to explore whether symptoms of sexual dysfunction are associated to hypogonadism.
Objectives
Participants were 165 subfertile men in infertile heterosexual relationships, 18–50 years of age, with sperm concentrations < 15 × 10...
Background
Erectile dysfunction (ED) has common risk factors with many cardiovascular (CV) impairments. In view of these facts, hyperhomocysteinemia (HHcys) has been postulated for involvement in endothelial dysfunction.
Objectives
We evaluated peripheral and penile homocysteine (Hcys) plasma levels before and after folic acid supplementation in idiopathic vasculogenic erectile dysfunction (ED)...
Background
Diet plays an important role in health and is a modifiable risk factor for chronic diseases. In men, sex steroid hormones influence, and are influenced by, a number of health states. Specific dietary patterns have been found to alter sex steroid hormone levels in observational and intervention studies. Thus, we hypothesized that dietary patterns captured by the Healthy Eating Index (HEI)...
Background
Sperm chromatin integrity is essential for normal embryo development and pregnancy outcome. Sperm DNA fragmentation (SDF) testing constitutes a diagnostic tool to measure the proportion of spermatozoa with damaged chromatin in the ejaculate. SDF is associated with potentially treatable conditions, including varicocele, male accessory gland infections, inadequate lifestyle, and gonadotoxin...
Background
Erectile dysfunction is defined as inability to achieve or maintain penile erection sufficient for sexual satisfaction. It is a serious problem that increases by age. The physiology of penile erection depends mainly on nitric oxide release.
Objectives
Compare the efficacy and safety of oral sildenafil 50 mg alone or in combination with l‐arginine 3 g/day orally on the treatment of erectile...
Background
In attempting to formulate potential WHO guidelines for the diagnosis of male infertility, the Evidence Synthesis Group noted a paucity of high‐quality data on which to base key recommendations. As a result, a number of authors suggested that key areas of research/evidence gaps should be identified, so that appropriate funding and policy actions could be undertaken to help address key...
Background
The presence of miRNAs in human reproductive tissue is intriguing and suggests the possibility that these important regulatory molecules play a role in reproductive function. However, the regulatory role of miRNAs in reproductive tissue remains poorly understood with a significant amount of controversial and contradicting data.
Objectives
To systematically review the high‐quality studies...
Background
The growing international movement legislating medical marijuana has brought renewed interest to the role of marijuana smoking on fertility potential. Although studies have identified that sperm quality can be compromised by marijuana use, little focus has been placed specifically on those trying to conceive. In this study, we aimed to clarify the impact of marijuana use in semen quality...
Introduction and objectives
Adult undescended testicles (UDTs) often present to fertility specialists with subfertility or azoospermia and with either an intra‐abdominal or inguinal testicle(s). Performing an orchidopexy followed by a surgical sperm retrieval (SSR) is a potential option to retrieve spermatozoa. A microdissection TESE (mTESE) procedure is performed to retrieve mature spermatozoa for...
Background
The association of leukocytospermia with male fertility is still under debate.
Objective
To evaluate the impact of leukocytospermia (≥1 × 106 white blood cells/mL of semen, according to the World Health Organization) in men attending a fertility clinic for couple subfertility, on fertility outcomes after assisted reproductive technology (ART) and on semen quality.
Materials and Methods...
Background
The possible role of phosphodiesterase 5 inhibitors (PDE5Is) in prevention of negative effect of diabetes mellitus (DM) on erectile function is not well settled.
Objectives
To investigate the effect of early administration of vardenafil on erectile function, cavernosal structure, and genes expression in a rat model of DM.
Materials and methods
This experimental study was carried out...
Background
Cryoprotective agent (CPA) addition during sperm cryopreservation causes detrimental effects on sperm function and quality. We previously reported that CPA addition adversely affects bull sperm physiological functions and shows differentially expressed proteins.
Objectives
To study functional and proteomic alterations between high CPA‐tolerant spermatozoa (HCS) and low CPA‐tolerant spermatozoa...
Background
Among new therapies emerging in the medical field, the use of platelet‐rich plasma (PRP) in human reproduction has not yet been explored.
Objectives
This study aimed at investigating the effect of autologous PRP on sperm parameters in the presence and absence of H2O2.
Materials and methods
Semen samples were collected from 30 healthy men in their fourth decade attending Azoury IVF...
Background
Despite widespread occurrence and poor comprehension, prostatitis has been largely under‐researched.
Objective
To compare complaints, general and sexual health, co‐morbidities, risk factors, and lifestyle in men with and without prostatitis‐like symptoms (PLS).
Material and methods
The cross‐sectional study included 20‐ to 59‐year‐old male residents of Estonia. Questionnaire data of...
Background
Limited studies have explored the association between gaseous pollutant exposures and male reproductive outcomes, and findings remained inconsistent.
Objectives
To evaluate the potential association between gaseous pollutants and semen quality within different exposure windows.
Materials and Methods
We adopted semen quality data of 1852 subjects who attended the Reproductive Medicine...
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